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Image Search Results
Journal: Neuropharmacology
Article Title: A role for hippocampal PSA-NCAM and NMDA-NR2B receptor function in flavonoid-induced spatial memory improvements in young rats
doi: 10.1016/j.neuropharm.2013.12.003
Figure Lengend Snippet: Levels of PSA-NCAM in the Dentate Gyrus of the Hippocampus. Levels of polysialylated NCAM cell frequency in the dentate gyrus of the hippocampus of adult Wistar Rats after 3 weeks of flavonoid supplementation. Animals treated with 17.4 mg of flavonoids ( n = 5) showed a significant increase in the frequency of PSA-NCAM cells compared to animals on the control diet ( n = 4) (** p < 0.01). Illustrative qualitative images of PSA immunoreactivity in the dentate granule cell layer/hilar border (GCL) at −5.6 mm with respect to bregma are presented (1 animal from the control group and 1 animal from the 17.4 mg flavonoid group). The green staining indicates the position of the immunostained cells at the infragranular zone and the scale bar represents 50 μm. Cell identification was aided by the use of the nuclear counter-stain propidium iodide (red). Cell counts were standardized to unit area of granule cell layer. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)
Article Snippet: Three groups of 8-week old experimentally
Techniques: Control, Staining